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Search Results for " myeloperoxidase inhibitor 1 "

9

Compounds

Cat No. Product Name Synonyms Targets
T26389 4-POBN NSC-640,NSC640,4-Aminobenzohydrazide,NSC 640,Myeloperoxidase Inhibitor 1,4-ABAH Glutathione Peroxidase
4-POBN (Myeloperoxidase Inhibitor 1) is a potent and irreversible inhibitor of myeloperoxidase (IC50 = 0.3 µM). 4-POBN can be used in studies about subacute stroke.
T40137 MPO-IN-1
MPO-IN-1 is a powerful and orally bioavailable indole-containing inhibitor that acts irrevocably on myeloperoxidase (MPO). With IC50 values of 2.6 μM and 5.3 μM for MPO and thyroid peroxidase (TPO), respectively, MPO-IN-...
T61711 COX-2-IN-14
COX-2-IN-14 (compound 2a) is a highly potent and selective inhibitor of COX-2 (cyclooxygenase-2), with strong binding affinity at the active site of COX-2 co-crystal. Demonstrating remarkable in vivo anti-inflammatory ac...
T62347 MPO-IN-5
MPO-IN-5 is a potent, irreversible inhibitor of MPO (myeloperoxidase). MPO-IN-5 inhibits MPO peroxidation (IC50: 0.22 μM) and hERG binding (IC50: 2.8 μM). 23000 M 1s 1.
T75618 Sorbifolin
Sorbifolin, a flavone glucoside isolated from Pterogyne nitens, exhibits myeloperoxidase (MPO) inhibitory and radical scavenging activities. This compound functions as an effective MPO inhibitor, demonstrated by its IC 5...
T38384 Nexinhib20
Nexinhib20 is an inhibitor of the protein-protein interaction between the small GTPase Rab27a and its effector JFC1 (IC50 = 2.6 μM).[1] It inhibits myeloperoxidase (MPO) secretion induced by granulocyte macrophage colony...
T60281 MPO-IN-4
MPO-IN-4 (compound 12) is a potent and selective myeloperoxidase (MPO) inhibitor with an IC 50 of 25 nM. MPO-IN-4 also demonstrates inhibition of thyroid peroxidase (TPO) with IC50 of 2.2 μM. MPO-IN-4 has no effect on me...
T37270 9(E),11(E)-12-nitro Conjugated Linoleic Acid
9(E),11(E)-12-nitro Conjugated linoleic acid (9(E),11(E)-12-nitro CLA) is a nitrated fatty acid. It is formed from 9(Z),11(E)-CLA upon exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combinat...
T36418 O-Desmethyl-N-deschlorobenzoyl Indomethacin
O-Desmethyl-N-deschlorobenzoyl indomethacin is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor indomethacin .1It is formed from indomethacin in isolated rabbit hepatocytes. O-Desmethyl-...
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